Why Traditional Treatments Sometimes Aren't Enough

Sinus Surgery: Surgery can correct physical obstructions of the paranasal sinuses and restore mucociliary clearance. But if the adherent, cilia-destroying bacterial biofilm is not removed from the site of infection, inflammation will persist and your patient's symptoms will return.

Antibiotics: Oral and topical antibiotics are ineffective for a number of reasons: (1) The slimy outer EPS layer acts as a physical barrier that inhibits antibiotic diffusion into the biofilm community, (2) Many antibiotics are designed to treat rapidly multiplying planktonic bacteria, and have little or no mode of action against slow-replicating bacteria in a biofilm, and (3) Bacteria in biofilms exhibit stress-response genetic pathways that confer antibiotic resistance. 12

Antifungals: Chronic sinusitis is not strictly a fungal disease. Healy et al. demonstrated that fungal elements are often present in bacterial biofilms in the sinuses5. Antifungals may clear fungus from the sinuses, but do not destroy the biofilm, and the patient's chronic sinusitis symptoms will eventually return.

Steroids: Steroid treatment provides temporary relief to chronic sinusitis patients because it helps to reduce inflammation. Steroids, however, are not antimicrobial, and the patient's symptoms will recur if the bacterial biofilm is not removed.

The Hydrodebrider® Treatment

Last update: 1 October 2009

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